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Corporate Profile

Scholar Rock is a clinical-stage biopharmaceutical company focused on the discovery and development of innovative medicines for the treatment of serious diseases in which signaling by protein growth factors plays a fundamental role. Our most advanced product candidate, apitegromab (SRK-015), a selective first-in-class inhibitor of the activation of the growth factor myostatin in skeletal muscle, is currently in development for the treatment of spinal muscular atrophy, or SMA. We are currently evaluating apitegromab in our TOPAZ Phase 2 proof-of-concept trial in patients with later-onset (Type 2 and Type 3) SMA. Positive six-month interim analysis results were announced in October 2020 and top-line data for the full 12-month treatment period are anticipated in the second quarter of 2021. In addition, we are conducting our DRAGON Phase 1 proof-of-concept trial for SRK-181, a highly specific inhibitor of latent TGFβ1 activation, in patients with locally advanced and metastatic solid tumors. We believe SRK-181 has the potential to overcome resistance and meaningfully increase the number of patients who may benefit from checkpoint inhibitors, such as anti-PD-1 or anti-PD-L1 therapies.

Utilizing our proprietary platform, we are creating a pipeline of novel product candidates with the potential to transform the lives of patients suffering from a wide range of serious diseases, including neuromuscular disorders, cancer, fibrosis and anemia.

News

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February 4, 2021

Scholar Rock Announces Senior Management Promotions

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January 27, 2021

Scholar Rock Presents Preclinical Data for SRK-181 at the TGFβ for Immuno-Oncology Drug Development Summit

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January 11, 2021

Scholar Rock Provides Corporate Update and Highlights Priorities for 2021

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Events

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March 1, 2021

Cowen 41st Annual Health Care Conference

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January 11, 2021 5:20 PM EST

39th Annual J.P Morgan Healthcare Conference

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December 1, 2020

Piper Sandler 32nd Annual Virtual Healthcare Conference

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SCHOLAR ROCK
620 Memorial Dr 2nd Floor
Cambridge, MA 02139

MOVING EARLY 2021 TO
301 Binney Street, 3rd Floor
Cambridge, MA 02142

Phone: 857.259.3860
info@scholarrock.com

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    Scholar Rock - Main navigation

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    • Oncology
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