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Corporate Profile

Scholar Rock is a clinical-stage biopharmaceutical company focused on the discovery and development of innovative medicines for the treatment of serious diseases in which signaling by protein growth factors plays a fundamental role. Our most advanced investigational product candidate, apitegromab (SRK-015), a selective inhibitor of the activation of the growth factor myostatin in skeletal muscle, is in development for the treatment of spinal muscular atrophy, or SMA. Apitegromab was evaluated in our TOPAZ Phase 2 proof-of-concept trial in patients with later-onset (Type 2 and Type 3) SMA and we shared positive 12-month top-line data demonstrating apitegromab’s therapeutic potential in April 2021. We initiated our SAPPHIRE Phase 3 registrational trial in patients with later-onset Type 2 and Type 3 SMA in November 2021. In addition, we are conducting our DRAGON Phase 1 proof-of-concept trial for SRK-181, a selective inhibitor of latent TGFβ1 activation, in patients with locally advanced and metastatic solid tumors. We believe SRK-181 has the potential to overcome resistance and meaningfully increase the number of patients who may benefit from checkpoint inhibitors, such as anti-PD-1 or anti-PD-L1 therapies.

Utilizing our proprietary platform, we are creating a pipeline of novel product candidates with the potential to transform the lives of patients suffering from a wide range of serious diseases, including neuromuscular disorders, cancer, fibrosis and iron disorders.

News

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March 15, 2023

Scholar Rock Reports New Employee Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

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March 7, 2023

Scholar Rock Reports Full Year 2022 Financial Results and Highlights Business Progress

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March 1, 2023

Scholar Rock to Present 24-Month Data from the Phase 2 TOPAZ trial at the 2023 Muscular Dystrophy Association (MDA) Clinical & Scientific Conference

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Events

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March 7, 2023 12:50 PM EST

Cowen 43rd Annual Health Care Conference

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January 10, 2023 1:30 PM PST

41st Annual J.P. Morgan Healthcare Conference

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November 29, 2022 8:00 AM EST

Piper Sandler 34th Annual Healthcare Conference

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SCHOLAR ROCK
301 Binney Street, 3rd Floor
Cambridge, MA 02142

Phone: 857.259.3860
info@scholarrock.com

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    Scholar Rock - Main navigation

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    • Spinal Muscular Atrophy
    • Oncology
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    • Iron-Restricted Anemia
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